Zebrafish Animal Model

In collaboration with a local industry, we were able to develop a 3D in vivo zebrafish model to predict metastatic potential in cells as well as determine drug efficacy and toxicity in a fast and cost-effective animal model. Using our zebrafish model, we have shown that breast cells expressing higher amounts of Spy1 have a higher metastatic potential and are more drug resistant. We are continuing to optimize and develop different drug toxicity, drug efficacy, and metastasis models in the zebrafish.